https://doi.org/10.1051/epjconf/202636601010
Synchronization in neuronal cultures
1 Laboratoire Matière et Systèmes Complexes, UMR CNRS 7057, Université Paris Cité, 10 Rue Alice Domon et Léonie Duquet, 75205 Paris Cedex 13
2 Integrative Neuroscience and Cognition Center,UMR 8002 CNRS, 45 rue des Saints-Pères, Université Paris Cité, 75270 Paris cedex 06
* e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Published online: 29 April 2026
Abstract
We have developed a model able to describe the experimentally observed activity behavior of 2D neuronal cultures as the coupling between neurons varies. As [Ca2+] in the medium increases, a gradual transition occurs from an asynchronous state in which neurons behave as independent oscillators, to a synchronous state where bursts of collective activity appear.
© The Authors, published by EDP Sciences, 2026
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