https://doi.org/10.1051/epjconf/201714302067
Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation
Brno University of Technology, Faculty of Mechanical Engineering, Energy Institute, Technicka 2896/2, Brno 616 69, Czech Republic
* Corresponding author: izal@fme.vutbr.cz
Published online: 12 May 2017
The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.
© The Authors, published by EDP Sciences, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
