https://doi.org/10.1051/epjconf/201819004022
Nanohybrid scaffolds with luminescent remote control
1
Institute of Bioorganic Chemistry RAS, 117997, Moscow, Russia
2
Scientific Research Centre “Crystallography and Photonics” RAS, 119333, Moscow, Russia
3
Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991 Moscow, Russia
4
N.N. Blokhin Russian Cancer Research Center of Ministry of Health of the Russian Federation, 115478, Moscow, Russia
5
Institute of Fine Chemical Technologies, Moscow Technological University, 119571, Moscow Russia
* Corresponding author: ddraig@yandex.ru
Published online: 26 September 2018
We report on hybrid nanocomposite scaffolds on the base of cross-linked hyaluronic acid derivative with embedded upconversion nanoparticles (UCNPs). The unique photoluminescence properties of specially designed hydrophilic UCNPs enable visualization of hydrogel using NIR irradiation. Formation of scaffold structure can be produced by means of 3D printing or direct laser writing. For the first time, we present visualization of nanohybrid scaffolds in live small animal aiming to demonstrate new possibilities of their luminescent remote control for tissue engineering.
© The Authors, published by EDP Sciences, 2018
This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
