UV-photochemistry of the biologically relevant thiol group and the disulfide bond: Evolution of early photoproducts from picosecond X-ray absorption spectroscopy at the sulfur K-Edge
1 Department of Physics, University of Hamburg and Max Planck Institute for the Structure and Dynamics of Matter, Center for Free Electron Laser Science, 22761 Hamburg, Germany
2 Ultrafast X-ray Science Lab, Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720
3 Department of Chemistry and Chemistry Institute of Functional Materials, Pusan National University, Busan 46241, South Korea
4 Center for Free-Electron Laser Science, DESY and The Hamburg Centre for Ultrafast Imaging, 22607 Hamburg, Germany
* Corresponding author: firstname.lastname@example.org
Published online: 16 April 2019
We report on the UV-induced photochemistry of the biologically relevant sulfur-containing thiol group and the disulfide bond in solution using picosecond X-ray absorption spectroscopy at the sulfur K-edge. This study provides element-specific insight into the 267-nm induced photo-chemistry of two model compounds, an aromatic thiol and an aliphatic disulfide. Our transient spectra point to two primary and several secondary photoproducts, and our analysis may aid in understanding UV damage in proteins.
© The Authors, published by EDP Sciences, 2019
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