https://doi.org/10.1051/epjconf/202023812010
Optical design of a variable angle irradiation system for skin cancer laser phototherapy
1 Departamento de Física, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal
2 Laboratório de Óptica, Lasers e Sistemas, Faculdade de Ciências, Universidade de Lisboa, Portugal
3 Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisboa, Portugal
* Corresponding author: dmm.garcia@campus.fct.unl.pt
Published online: 20 August 2020
Photothermal therapy is a developing therapeutic technic mainly regarding the usage of nanoparticles considering their proneness to assemble around malignant tissue and induce their destruction by converting electromagnetic radiation into thermal radiation. In order to optimize this process, controlling the area of incidence in a way that it can fit the tumour and prevent damage of healthy cells is of great importance. This study was conducted by designing an optical system based on zoom systems for manipulating an initial input beam and adjust it to the most common skin cancer sizes. Two solutions are proposed, accomplishing spot sizes at 150 mm from the last lens within the approximate range of 2 mm to 76 mm, with beam divergences lower than 3 mrad.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
