https://doi.org/10.1051/epjconf/202226604001
Polarization Sensitive Digital Holographic Imaging in Biology
1 National Research Council, Institute of Applied Sciences and Intelligent Systems ‘E. Caianiello’, Unit of Naples, 80131 Naples, Italy
2 National Research Council, Institute of Experimental Endocrinology and Oncology ‘G. Salvatore’, 80131 Naples, Italy
* Corresponding author: antonella.ferrara@na.isasi.cnr.it
Published online: 13 October 2022
A new, simple digital holography-based polarization microscope for quantitative birefringence imaging of biological cells is presented. As a proof of concept, two different class of cells have been characterized by polarization sensitive digital holographic imaging (PSDHI). These two cases study reported are: differentiation of leukaemia cells and identification of reacted sperm cells. Although further experimentation is necessary, the suggested approach could represent a prospective label-free diagnostic tool for use in biological and medical research and diagnosis.
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