https://doi.org/10.1051/epjconf/202329008001
Radiobiology experiments with a laser driven x-ray source: Exploring the UHDR regime
1 Instituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Spain.
2 Instituto de Instrumentación para Imagen Molecular (I3M), CSIC - Universitat Politècnica de València, Spain.
3 Fundación Pública Galega de Medicina Xenómica (FPGMX), Instituto de Investigación Sanitaria de Santiago de Compostela, Spain.
4 Instituto de Física Fundamental y Matemáticas, Universidad de Salamanca, Spain.
* email: alicia.reija@rai.usc.es
Published online: 8 December 2023
Laser Driven Plasma Accelerators (LDPA) can generate both characteristic and Bremsstrahlung x-rays in ultrashort bunches. Because of the high intensity of the laser pulses, these laser-induced x-ray sources can achieve peak dose rates compatible with the FLASH regime. At the Laser Laboratory for Acceleration and Applications (L2A2/USC), a setup for the irradiation of in vitro cell cultures with a laser-driven x-ray source has been developed. The suitability of this source for studying the influence of Ultra High Dose Rates (UHDR) on DNA damage has been proven through the irradiation of in vitro cell cultures.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
