https://doi.org/10.1051/epjconf/202430904015
Optimizing Plasmonic Microarray Biosensors: Custom Optical System for Enhanced Evaluation and Characterization
1 Optimal Optik Ltd., Dayka Gábor u. 6/b, 1118 Budapest, Hungary
2 Leibniz Institute of Photonic Technology, (Leibniz-IPHT) Department Nanobiophotonics A.-Einstein-Str. 9, 07745 Jena, Germany
3 Budapest University of Technology and Economics, XI. Magyar tudósok körútja 2. I ép. E szárny, H-1117 Budapest, Hungary
* e-mail: csoke.lorant@edu.bme.hu
** e-mail: andrea.csaki@leibniz-ipht.de
*** e-mail: kollarzs@mit.bme.hu
Published online: 31 October 2024
This paper presents the design and implementation of a tailored optical system for rapid characterization of transmission-based localized surface plasmon resonance (LSPR) biosensors. The system incorporates a motorized monochromator, offering extreme versatility in experimenting with wavelength resolution and bandwidth of the illumination. This setup streamlines the process of determining optimal chip design parameters such as the density of nanoparticles and the number of detection wavelengths required, as measurements are fully automated and software-driven. Furthermore, the system facilitates straightforward detection of manufacturing errors, including misaligned spots or inhomogeneous particle distribution, enhancing overall efficiency and reliability in biosensor evaluation.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
