https://doi.org/10.1051/epjconf/202328703006
Femtosecond laser rapid prototyping and characterization of microfluidic device for particles sorting
1 Physics Department, University & Polytechnic of Bari
2 IFN-CNR, Bari ;
3 IFN-CNR, Milano
* Corresponding author: author@e-mail.org
Published online: 18 October 2023
Rapid prototyping methods for the fabrication of polymeric labs-on-a-chip (LoC) are on the rise, as they allow high degrees of precision and flexibility. In this contest, the flexibility of ultrafast laser technology enables the rapid prototyping and high-precision micromachining of 3D LoC devices with complex microfluidic channel networks. In this paper, we describe the realization process of a microfluidic tool for fully inertial particles sorting. The microfluidic network was realized in polymethyl methacrylate (PMMA), exploiting femtosecond laser technology. The multilayer device was assembled through a facile and low-cost solvent-assisted method. In particular, we studied the particle focusing in curved inertial microfluidic channel with trapezoidal cross section. A particles focusing along the walls of the device, sensitive to particle size and flow rate, was observed based on the principle of Dean-coupled inertial migration in spiral microchannel.
© The Authors, published by EDP Sciences, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
